I kind of liked the idea to get one camera system and use it throughout the career. Even expensive systems like medium format are quite okay that way. I'm not really interested jumping between "current best" every 3-4 years. Unfortunately I bet on the wrong horse and the MF industry seems to have chosen to slowly kill the tech cam genre, but it hasn't increased my want for other cameras. Shooting large format film may be the most suitable future option for me, which has actually caused me to be less interested in live view and other digital convenience features as it makes me less prepared to shoot film.
I'm always interested in new products from an engineering and business perspective though.
Wildlife photography, especially video, has really evolved thanks to technology with ultra-high sensitivities, super telezooms, remote controlled lightweight camera systems, drones etc. When it comes to more static genres like landscape, portraits etc I don't really see that the past 10 years technical development has contributed much to evolve the styles. For landscape we've got dynamic range and HDR.
So "game changing" in terms of how we make pictures in highly unlikely. But it could be game-changing in terms of MF pricing and accessability for example. An attractively priced mirrorless 44x33 camera body with short enough flange distance so it can take virtually everything could be the next "A7r-II", on every landscape enthusiast's wishlist and many pro photographers that use Actus etc for tech photography. If it's a panoramic camera with quite long flange distance I don't expect it to be as popular.