I don't understand how apps relate to the Epson print driver.
Is the print dialog in ACPU a barebones version of the Epson print driver?
If it is, then when we use it to print Doug's ball target (or a slither of it, to save ink), at 8 bit and at 16 bit, we thereby demonstrate (to the OP) that there is a visible difference in Epson's 8 bit and 16 bit printing pipeline.
We can't do this with Photoshop*, because when printing from Photoshop, the Epson driver utilises Photoshop's dithering algorithm, which makes an 8 bit print of a 16 bit file looks identical to a 16 bit print. (*Unless we switch off dithering in Color Settings.)
Right?
(All my test prints from Photoshop have been done using 'Photoshop Manages Colors'. Whether 'Printer Manages Colors' handles 16 bit gradients in the same way is another can of worms.)