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Author Topic: Promising New Coronavirus Vaccine  (Read 107058 times)

Slobodan Blagojevic

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Re: Promising New Coronavirus Vaccine
« Reply #140 on: February 28, 2021, 03:06:51 am »

Savage! 😂

LesPalenik

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Re: Promising New Coronavirus Vaccine
« Reply #141 on: February 28, 2021, 04:52:46 am »

Czech Republic has initially controlled covid spread very effectively, but in the last 5 months the virus got out of control, and now the country has six times as many cases as USA (per capita). There are no tourists in the country and Old Town in Prague is eerily empty, ideal for photographing empty streets and squares.

Quote
Nearly a year after the start of the coronavirus pandemic, the Czech Republic has the highest per capita rate of new Covid-19 cases in the EU, with 107,777 cases per million inhabitants, the Czech News Agency reported on Sunday.

Globally, it is the most affected country by coronavirus, after Andorra and Montenegro. The Czech Republic also places third in the EU and fourth in the world in terms of per capita number of Covid-19 deaths, with just under 1,800 deaths per million inhabitants.

Over 1.1 million cases of the virus have been confirmed in the country since the virus was first registered in the country on March 1, 2020. To date, 19,214 people infected with coronavirus have died in the Czech Republic.
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faberryman

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Re: Promising New Coronavirus Vaccine
« Reply #142 on: February 28, 2021, 07:32:33 am »

New study on hydroxychloroquine:

"HCQ and HCQ/AZ are not effective therapies for outpatient treatment of SARV-CoV-2 infection"

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(21)00053-5/fulltext
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jeremyrh

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Re: Promising New Coronavirus Vaccine
« Reply #143 on: February 28, 2021, 07:42:13 am »

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jeremyrh

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Re: Promising New Coronavirus Vaccine
« Reply #144 on: February 28, 2021, 07:47:07 am »

Why isn't anyone blaming China?  That's where it started and that's where it was deliberately hidden from the rest of the world.  Why is everyone blaming the victims?  We're trying to do the best we can under a horrendous situation where you're damned if you do and damned if you don't.

Everyone knows and agrees on China's role - what's to discuss? The victims are the 500k dead Americans, the 120K dead Britons etc etc most of whom died needlessly due to the incompetence of their leaders.
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Alan Klein

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Re: Promising New Coronavirus Vaccine
« Reply #145 on: February 28, 2021, 09:49:09 am »

Do you mean for not closing down its "wet markets?"  Western governments and non-governmental organizations have been urging that for many years, but it's not just China: the markets where live animals cohabit exist in many Asian countries.  It's difficult to change ingrained cultural traditions and the only practical response to venues which breed interspecies propagation of pathogens in a global travel environment may be better preventative and therapeutic medical technology.
No, that's dismissing all their deliberate malfeasance, possibly criminal.  It appears it was released from the lab coincidentally located in Wuhan, the center of the disease.  So they are responsible for negligence at a minimum.   Worse, they allowed infected Chinese to travel to the rest of the world while quarantining their own country shutting down intra-country travel from Wuhan. They knew the dangers otherwise they would not have quarantined Wuhan.  Then they lied about the whole danger of the disease for weeks when the world could have gotten a jump on it. 

Alan Klein

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Re: Promising New Coronavirus Vaccine
« Reply #146 on: February 28, 2021, 09:52:26 am »

Most definitely, China is the culprit. But they don't want to argue.
Interestingly, they stopped reporting new cases and deaths. Did they reach herd immunity or how do you explain that?
They're a police state. They even lock sick people in their homes and beat them up if they don't comply with rules and regulations.  Would you accept that in Canada?

Alan Klein

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Re: Promising New Coronavirus Vaccine
« Reply #147 on: February 28, 2021, 09:55:11 am »

Czech Republic has initially controlled covid spread very effectively, but in the last 5 months the virus got out of control, and now the country has six times as many cases as USA (per capita). There are no tourists in the country and Old Town in Prague is eerily empty, ideal for photographing empty streets and squares.

They should invite the Chinese Army in to straighten them out and set them right.

Alan Klein

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Re: Promising New Coronavirus Vaccine
« Reply #148 on: February 28, 2021, 09:58:25 am »

Everyone knows and agrees on China's role - what's to discuss? The victims are the 500k dead Americans, the 120K dead Britons etc etc most of whom died needlessly due to the incompetence of their leaders.
What did Britain do that was negligent?  I'm not familiar with the situation there. Were they listening to Trump?  In any case,  I have read their vaccination program is better than anyone else's.  So there's that.

jeremyrh

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Re: Promising New Coronavirus Vaccine
« Reply #149 on: February 28, 2021, 10:08:46 am »

What did Britain do that was negligent?  I'm not familiar with the situation there. Were they listening to Trump?  In any case,  I have read their vaccination program is better than anyone else's.  So there's that.

So many things - too slow to lock down even when they had the example of Italy to see what would happen, didn't close borders, didn't have an effective tracing system, didn't support people to stay at home and isolate with covid, opened up too soon, allowed too much travel over Christmas. Much the same as Trump I suppose. They got it right with ordering a lot of vaccine and in giving it to the NHS to distribute instead of their cronies who got a lot of the other big contracts.
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LesPalenik

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Re: Promising New Coronavirus Vaccine
« Reply #150 on: February 28, 2021, 10:30:54 am »

They're a police state. They even lock sick people in their homes and beat them up if they don't comply with rules and regulations.  Would you accept that in Canada?

Do they really beat people? Maybe it's just sexual role playing. Or did they send out a dominatrix brigade?
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Alan Klein

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Re: Promising New Coronavirus Vaccine
« Reply #151 on: February 28, 2021, 10:32:11 am »

So many things - too slow to lock down even when they had the example of Italy to see what would happen, didn't close borders, didn't have an effective tracing system, didn't support people to stay at home and isolate with covid, opened up too soon, allowed too much travel over Christmas. Much the same as Trump I suppose. They got it right with ordering a lot of vaccine and in giving it to the NHS to distribute instead of their cronies who got a lot of the other big contracts.
Maybe the government was doing pretty much what the people wanted.  Also, they were caught between a rock and a hard place.  Britain was already dealing with Brexit and its economic problems. The last thing you needed was Covid to make it worse.  So you try to balance maintaining economic conditions so people can feed themselves vs. risking the spreading of disease.  Also, it's easy to Monday morning quarterback the game after it's over.  We should have done this.  We should have done that.  Stop "should-ing" on yourself. At least you did some things better, such as the vaccinations.  You should be happy and proud of that.

Robert Roaldi

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Re: Promising New Coronavirus Vaccine
« Reply #152 on: February 28, 2021, 12:41:45 pm »

...  It appears it was released from the lab coincidentally located in Wuhan, the center of the disease.  So they are responsible for negligence at a minimum.  ...

Is this a true fact or a made-up fact?
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Alan Klein

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Re: Promising New Coronavirus Vaccine
« Reply #153 on: February 28, 2021, 01:11:30 pm »

Is this a true fact or a made-up fact?
International incidents don't get tried in a court of law.  We all make decisions based on available information and logic.  The lab was in Wuhan working on this virus.  That's where the disease started.  The Chinese want you to believe it started in a food market. You could believe whatever you want. 

We have to make decisions as a country on how we deal with other countries.  Did Salman order the death of Khashoggi? He denies it.  The CIA says they believe he was responsible although they also have no conclusive evidence, just strong reasoned judgment.  Most international affairs decisions are not based on evidence being represented in a court of law.  We have to make reasoned judgments.  Even if it was naturally released in a market, they still lied to the world about it and continued to send infected Chinese to travel to infect the rest of the world.  The lab is just part of the issue with them.

jeremyrh

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Re: Promising New Coronavirus Vaccine
« Reply #154 on: February 28, 2021, 01:20:23 pm »

Is this a true fact or a made-up fact?

It's an Alan fact.
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Alan Klein

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Re: Promising New Coronavirus Vaccine
« Reply #155 on: February 28, 2021, 01:40:34 pm »

It's an Alan fact.
What's your fact? That Trump killed half a million people?

TechTalk

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Re: Promising New Coronavirus Vaccine
« Reply #156 on: February 28, 2021, 01:46:22 pm »

We all make decisions based on available information and logic.

Oh, how I wish that was actually a fact.
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TechTalk

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Re: Promising New Coronavirus Vaccine
« Reply #157 on: February 28, 2021, 01:48:21 pm »

You could believe whatever you want. 

Now that's a well proven fact!
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josh.reichmann

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Re: Promising New Coronavirus Vaccine
« Reply #158 on: February 28, 2021, 02:06:57 pm »

Steer the thread back to the topic of “promising new coronavirus vaccine” or shuttle the overtly political to the one and only political thread.
Thanks.
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TechTalk

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Re: Promising New Coronavirus Vaccine
« Reply #159 on: February 28, 2021, 02:42:09 pm »

A recent and fairly lengthy article on the new Johnson & Johnson vaccine with some comparison to the Pfizer and Moderna vaccines.

Full article link

https://www.statnews.com/2021/02/02/comparing-the-covid-19-vaccines-developed-by-pfizer-moderna-and-johnson-johnson

Selected excerpts below

On Feb. 27, the Food and Drug Administration announced it had issued an emergency use authorization for Johnson & Johnson’s one-dose Covid vaccine. Developed by J&J’s vaccines division, Janssen Pharmaceuticals, it was shown to be 66% protective against moderate to severe Covid infection in a multi-country study. Importantly, it was 85% effective in protecting against severe disease. And there were no hospitalizations or deaths among people in the vaccine arm of a large clinical trial.

Overall efficacy varied a bit geographically, especially in South Africa, where a new variant appears to evade to some degree the immunity induced both by infection and by Covid vaccines, which were designed to target earlier strains of the SARS-CoV-2 virus.

The Pfizer and Moderna vaccines are made using messenger RNA, or mRNA, a technology that delivers a bit of genetic code to cells — in effect, a recipe to make the surface protein (known as spike) on the SARS-2 virus. The proteins made with the mRNA instructions activate the immune system, teaching it to see the spike protein as foreign and develop antibodies and other immunity weapons with which to fight it.

The J&J vaccine uses a different approach to instruct human cells to make the SARS-2 spike protein, which then triggers an immune response. It is what’s known as a viral vectored vaccine. A harmless adenovirus — from a large family of viruses, some of which cause common colds — has been engineered to carry the genetic code for the SARS-2 spike protein. Once the adenovirus enters cells, they use that code to make spike proteins.  J&J employed this same approach to make an Ebola vaccine that has been authorized for use by the European Medicines Agency.

Because of the difference in the trials, making direct comparisons is a bit like comparing apples and oranges. Additionally, Pfizer and Moderna’s vaccines were tested before the emergence of troubling new variants in Britain, South Africa, and Brazil. It’s not entirely clear how well they will work against these mutated viruses.

The J&J vaccine was still being tested when the variants were making the rounds. Much of the data generated in the South African arm of the J&J trial involved people who were infected with the variant first seen in South Africa, called B.1.351.

The J&J one-dose vaccine was shown to be 66% protective against moderate to severe Covid infections overall from 28 days after injection, though there was variability based on geographic locations. The vaccine was 72% protective in the United States, 66% protective in South America, and 57% protective in South Africa.

But the vaccine was shown to be 85% protective against severe disease, with no differences across the eight countries or three regions in the study, nor across age groups among trial participants. And there were no hospitalizations or deaths in the vaccine arm of the trial after the 28-day period in which immunity developed.

It’s not yet known if any of these vaccines prevent asymptomatic infection with the SARS-CoV-2 virus. Nor is it known if vaccinated people can transmit the virus if they do become infected but don’t show symptoms.
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