The banding I'm seeing is very subtle. It is significantly less than the banding visible when the image is printed after being converted in Photoshop to 8 bit (with no dither). But it does indicate that the 16 bit checkbox in the Epson print dialog is not merely cosmetic - it does do something, and it should remain checked.
Glad you reported this as something now is going on that is VERY odd.
I took a profile target with 918 patches hoping to make a print with check box on and off, nothing more, so I could measure and produce a colorimetric report. I printed the targets
three times and I keep seeing this which is rather alarming.
Before I paste the report, again, this is 918 patches of differing colors I can measure on my iSis. I printed it 'untagged' (the assumption would then be ProPhoto RGB) but also assigned sRGB to the target. The original wasn't in 16-bit so I converted it as such. That alone shouldn’t be an issue. Again, everything is identical between the two prints going off to the Epson 3880
expect the check box for 16-bit is either ON or OFF in the driver. This is the difference which is huge:
Number of Samples: 918
Delta-E Formula dE2000
Overall - (918 colors)
--------------------------------------------------
Average dE: 11.16 Max dE: 42.30
Min dE: 0.21
StdDev dE: 7.14
95th %ile dE: 15.22
Best 90% - (825 colors)
--------------------------------------------------
Average dE: 9.33
Max dE: 20.13
Min dE: 0.21
StdDev dE: 4.47
Worst 10% - (93 colors)
--------------------------------------------------
Average dE: 27.40
Max dE: 42.30
Min dE: 20.13
StdDev dE: 5.73
--------------------------------------------------
Doug, I believe you have a printer from Epson with this option and I know you too can print and measure as I did. I need a major reality check here. The max dE (42) and the most egregious differences are in green. But even the average is alarming and I don't know if this might be a bug with Mojave, the driver, but it's very strange.
And now that I examine the two prints I made today, using Doug's construct, I do notice the gray balance is a bit different visually. With lots of colors, it's all over the map. The targets were 'wet', right out of the printer so the dE's would be a tad lower tomorrow but nothing is going to get the two close to where they should be.
I suppose I should also try the same test but use my Gamut Test File image which is natively 16bit and print one each with (check box off and on), the difference in colors should be visible. If anyone with a 3880 can test this, it would help. I suppose it could be the driver acting up with the new OS as I can't believe the check box would make such a huge difference. I can see the differences of the color patches, there was little need to measure them but none the less, we can see the huge colorimetric differences. So anyone with this printer on Mac running Mojave can test this without the need of a Spectrophotometer. Look at greens. The lowest dE is a middle gray (0.21). So the black ball is in an area of color space (neutrals so to speak) where the color differences are the least. The driver I'm using for the Mac is 9.33, I can't find anything newer.
Odd, very very odd!