I would suggest this can be done, but the caveat is that you need enough printable area in the right places to facilitate it. As neile notes, the bottom unprintable area (0.91") is larger than the unprintable area for the other three sides (0.20"). This means there is not enough printable area on an 8.5x11 sheet to even print an 8x10 image, much less print it centered. However, you should be able to print that same 8x10 image centered (for example) on an 11x14 sheet. That may not be practical, unless you like large margins. I generally position multiple images on a roll and later trim to size.
Terry.