If you want a preset that, for example, is just a setting to get a Fuji Neopan 400 with a red filter, then:
1) Select a raw file to set up the preset.
2) Select the preset "General Purpose Preset - #4 - No Correction." This will disable all automatic/default corrections.
3) Now select the Black and White film sim and filter combination you want (for example, Fuji Neopan 400, red filter).
4) Select the menu item "Image > New preset from current settings..." and name it something useful.
5) Done!
Now when you open a new image and apply the preset, it will turn off all of the Default corrections and only apply the film sim+filter correction. If you enable further corrections (like Exposure, Smart Lighting, etc.) then you will need to inspect the settings on that particular palette to make sure no automatic corrections are enabled (if you do not want them to be).
Make sure to apply this preset before you start editing other settings - applying the preset after starting edits will wipe out those edits.
Kirk