Thanks guys, nothing wrong with the card reader. I did talk for 10 min with makers of PhotoResuce and this software is just antiquated mess.
Its design is awful, but impossible part if that is just cannot find the simple CD card on the dekstop. It has no option to choose the card (or whatever hardrive easily).
If anyone can please send links to great up to date, nicely designed card rescue, (ie finding deleted images) for CF cards, thanks!