As i understand you have a machine with 1 TB SSD ( this drive will do 2400MB/second)
and two Sata drives in the Drobo. One for backup and one for images.These drives will do 200MB /second.
The idea of the drobo is that with more disks you have a RAID with more speed and safety over your files. ( up to 300mb/sec and no risk of losing data due to faulty disks)
In general
You have a very fast compurter with a veryfast SSD connected to a a slow DROBO.
If your LR catalogue is on the Drobo it will be not the fast solution your iMac is capable of- you need something like this)
https://eshop.macsales.com/shop/express-4m2( the Drobo interface is fast , but the drives are slow)
1 it is clear you have to run your work on the 1TB SSD to get all the portential out of the iMac- or connect a LR catalogue stored on a pci-SSD.
2 Your backup should be larger than 5 TB - i would choose 8 TB at least. ( it has to backup the images (4TB) and the (1TB) SSD in time)
what I think is important:
safety of your files _
If you computer gets stolen what is left?
If you harddisk turns bad - what is left?
Make sure your backup takes all data for a length of time and have one extra in another physical place to reduce these risks.
- how do i use the potential of the machine i just bought.
Considering a 8TB sata disks cost about 200$ it is not the place to reduce costs.
It is personal choice how to deal with these potential problems.