Thanks Andrew. Since I was short on expertise and using a rented device due to be returned, I just tried to optimize one profile, out of the twelve I made, in a relatively automated way. For whatever it's worth, although the X-Rite software for the i1Studio has separate processes for making color and B&W printer profiles,* it only lets you optimize color profiles. So I took the profile I'd made for Mitsubishi Pictorico White Film on the Canon Pro-100 and optimized it, letting it use the maximum number (30) of additional patches it chose for itself from one of my images. After printing, drying, and measuring those additional patches, it spit out the optimized profile. For whatever little it might tell you, across two different printers, all the B&W profiles are 1584KB, all the color profiles are 1602KB, and the optimized color profile is 1607KB. Unfortunately I have not had time to do any printing with these profiles, so maybe the most important test remains to be performed.
*Interestingly to me, the B&W profiles use more target patches, with the second, semi-customized target containing an additional 100 patches, instead of an additional 50 patches for the color profile second target.