I am most likely in the minority here but here are my microdrives history and with other compact flash cards. In 2000, first bought a 340mb microdrive, have shot thousands if not tens of thousands of images on it since, still functional and used daily albeit less. Have 2 [1] gb microdrives, a 2gb microdrive bought in the last few yrs, all still working. Have sandisk [ultra II and reg]1 and 2 gb flash cards, have never had a missed image on any of them, never a failure. I know fellow digital photographers who have had both issues with CF cards and microdrives, especially Lexar which are sworn by by most shooters and reviewers, as being the best and most reliable. I am careful with my cards of all types, have dropped both a microdrive and others a few inches onto a hard desk surface without fault, but in general I treat them very well. If you are using them for travel, outside conditions etc, I would stick with Cf cards, why temp fate with moving parts, humidity etc, but if in studio usage and with care either would work fine. I am slowly picking up more CF cards over time, only because most of my important shooting as a hobbyist is with travel. Hope this helps.