Its certainly possible but why would this be related to this particular lens? I nearly always shoot with center focus using all lenses and I shoot manual when I think it will benefit the shot.
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I recently had the lens recalibrated in Jamesburg NJ,when I was there, I spoke to a pro sports photographer who was having his lens recalibrated as well.
He advised me to use manual mode on the camera ,when using L series lens,because of the focusing issues that these lenses have.
This sounded a little odd,so,that's why I'm posting the question.
I tried to verify this with one of the tech people at canon,but they would not let me speak to one.
99% of the time i use the AV mode.
Mike