I'd say yes potentially.
I recently implemented flat-field correction on a smartphone and it corrected with very convincing results both light fall off of various kind and color casts (aka awful pink spot as seen before on some products)
In this case, the light fall off was not looking like the typical vignette correction, and color cast was intense due to the physical constrains: the camera module being as small as possible, light ends up hitting the sensor with steep angles.
The task was made easier thanks to the fact it was on fixed a focal length and aperture lens, otherwise I suppose additional profiles + interpolation would have been necessary.