I'm a huge advocate of medium format on this board and elsewhere (I'm the Head of Technical Services for a large Phase One / Leaf dealer) and I agree with the rest of the recommendations here. If you absolutely cannot add more light to the scene then 5DII or D3X will be your best bet. If you could add just another couple stops of light then the medium format systems will start to mop the floor, especially the P65+ which has unbelievable resolution/color/DR. But if you cannot add another stop or two of shutter, aperture, or ambient light then this is not an easy job for a medium format system. Is there no way for you to add more light? e.g. strobes through existing window-light, replacing existing lower watt bulbs with higher watt bulbs?
No matter which route you go you should be VERY interested in trying different raw converters as not all programs which can open your files will show them with the same quality; this is especially true for higher ISO shots. Capture One, LightRoom, Irrident Raw Developer, etc etc should all be on your list to run a file or two through to make your own conclusions.
That said you did ask, so I'll offer a couple options in medium format
In the Leaf/Phase product line the leading high-ISO cameras are the P30+ (1600ISO@31mp) and P65+ in sensor plus mode (1600/3200ISO@15mp). The 15mp from the sensor plus files are pixel binned prior to the raw file from a 60 megapixel sensor with no AA filter and compare favorably to a 22-24 megapixel dSLR in actual resolved detail, but you're looking for higher resolution not favorable resolution. We have a
comparison on our website of the P40+ 10mp Sensor Plus files to the 5D2 at ISO800 - bare in mind when viewing that the P65+ Sensor Plus files are 50% larger.
We don't know about your subject/scene, but one strategy to think about would be shooting different "plates". If you're frame is mostly a static scene with people moving within it then set up on a tripod with a P65+ and shoot one plate of the overall static scene at 60 megapixels at ISO400* with longer shutter speed (highest of any digital back) and then with a simple button push you could shoot an ISO1600 plate at 15 megapixels with a longer lens to capture the people. Or you could lower the ISO and take one plate wide-open (subject in focus / environment OOF) and another plate with high enough aperture for the environment. I'd rather take single-frames than composite but the situation you're positing is not an easy one for any camera if your goal is top notch quality large prints.
*ISO400@60mp and ISO1600@15mp have very similar grain/contrast/color characteristics so the composite files would match
Doug Peterson
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Head of Technical Services, Capture Integration
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