How much more bothersome or difficult is it to carry and set up a digital view camera for landscape work? We know it's bigger and heavier
A 10 * 8 folding camera with one small lens is relatively light and compact - how heavy, how big?
An MFDVC (MediumFormat Digital View Camera) (e.g. Sinar F3) system is, I believe, no heavier than a 10 * 8 Camera system, particularly if your 10* 8 system includes long lenses, which weigh kilos each.
Set-up is easier if you cary a laptop and use live view... which you would not if weight was an issue.
You will need a very good loupe to focus on the small ground glass screen - I think most adaptor manufacturers supply them.