I've finally got to the point of upgrading my old Synology 421+ to a 1621xs with 6x16TB drives.
As I'm also switching most of my photo stuff to Mac via MacBook Pro, I intend to use it as my main storage to be accessed mostly via 10Gbe network.
So the question is what RAID should I use. As the capacity is well in excess of anything that I need in the foreseeable future (big sale on HDDs), I care about speed and redundancy. I was tempted by RAID 1+0 but if the Synology Hybrid Raid is fast enough to saturate the 10Gbe for read/write, I would go with it for more flexibility if an HDD dies. I did buy an extra one identical to those 6 but SHR would give me the flexibility to use different HDDs should the initial ones fail.