Promising New Coronavirus Vaccine

[Robert Roaldi]

Is there anything at all constructive still occurring for each of you in this thread? Is there even a thread?
Reflect and if the thread continues on coarse simply as a place where insults and revisited grievance is dominant then I see no reason to keep it going. Mental health is important. Take stock. Breath. Resume as you see fit.
Thanks

Well, there is precious little info on vaccines anymore.

[TechTalk]

What I would like to do is continue on the topic of Coronavirus Vaccines. I'm glad that Chris Kern started the thread on this topic as I'm interested in the ongoing developments. Restraint from diversions would likely be helpful in learning more about the thread's stated topic.

[Robert Roaldi]

What I would like to do is continue on the topic of Coronavirus Vaccines. I'm glad that Chris Kern started the thread on this topic as I'm interested in the ongoing developments. Restraint from diversions would likely be helpful in learning more about the thread's stated topic.

I'd vote for that option.

[Chris Kern]

. . . the chances of young people dying from Covid in current conditions (low level of infection in the community) are more or less zero.  That calculation may change, of course, if the level of infection rises.

While children and adolescents rarely die from COVID-19, and often exhibit no symptoms at all when infected by the SARS-CoV-2 virus, there is recent evidence that asymptomatic infections in young people may have other adverse consequences:

Question  What are the clinical characteristics and geographic and temporal distribution of multisystem inflammatory syndrome in children (MIS-C) in the United States?

Findings  In this cross-sectional study, 1733 patients with MIS-C were identified with predominantly gastrointestinal, mucocutaneous, and cardiovascular manifestations, and a majority required intensive care. MIS-C peaks closely followed the peaks of COVID-19 and the spread of the pandemic from urban to rural communities.

Meaning  The data are consistent with observations that MIS-C resulted from delayed immunologic responses to infection by SARS-CoV-2.

This somewhat complicates the risk-benefit assessment of which vaccines are most appropriate to administer to this segment of the population.

[Chris Kern]

Luckily there are alternative vaccines, but suppose there weren't?  How justified would it be to ask a young person to take a small risk in order to protect an old one. . . . What do you think?

I don't know enough to have an opinion.

[Manoli]

What I would like to do is continue on the topic of Coronavirus Vaccines. I'm glad that Chris Kern started the thread on this topic as I'm interested in the ongoing developments. Restraint from diversions would likely be helpful in learning more about the thread's stated topic.

On that theme then, I’d refer everyone to a new article in the NYT. Not new for Europeans and as yet, not prevalent in the USA but underlines the moving ‘window’ that this virus represents.

Rise of Variants in Europe Shows How Dangerous the Virus Can Be

[Chris Kern]

On that theme then, I’d refer everyone to a new article in the NYT. Not new for Europeans and as yet, not prevalent in the USA but underlines the moving ‘window’ that this virus represents.

Our genomic analysis efforts here in the United States are still rather pathetic, although they are becoming more extensive.  Based on the latest test results, the very aggressive B.1.1.7 variant first identified in the U.K. is now believed to be responsible for most new infections here as well as in Europe, and may account for why more people in their 30s and 40s are requiring hospitalization for COVID-19.

[Manoli]

Is there anything at all constructive still occurring for each of you in this thread? Is there even a thread?

Note to moderator:
There’s plenty of scope for this thread to serve as a useful noticeboard come pinboard for both developments in vaccines and the latest research into the virus itself, which I believe to be the intention of the OP. Effective moderation calls for intervention at times and eliminating notably uninformed  ‘grandstanding’  by some individuals.

There is a difference between ongoing scientific research and personalised ‘virus theory’ combined with lambasting the epidemiologists who are tasked to lead us through this pandemic.

[faberryman]

I read the other day that Brazil set a one day record of 3,780 COVID deaths. Just to put that in perspective using rough approximations, that would be something in the range of 40,000 COVID deaths in one day in the US. I think perhaps Trump's pal Jair Bolsonaro might want to revisit his response to the pandemic, but he appears to be more concerned with maintaining his support by the military.

https://www.cnn.com/2021/03/31/americas/brazil-bolsonaro-military-upheaval-covid-intl-latam/index.html

On the other hand, we could discuss the role, if any, of government in public health on a theoretical level.

[Manoli]

Our genomic analysis efforts here in the United States are still rather pathetic, although they are becoming more extensive.  Based on the latest test results, the very aggressive B.1.1.7 variant first identified in the U.K. is now believed to be responsible for most new infections here as well as in Europe, and may account for why more people in their 30s and 40s are requiring hospitalization for COVID-19.

Certainly, I’m hearing of ICU’s populated, in the majority, by the 20 to 35’s at least here in Athens. Whereas Greece was one of the outperformers in last year’s lockdown, the viral load, as measured daily by the Govt, has reached new highs, similar to the other Mediterranean countries.

I’ll PM you the rest.

[Alan Klein]

I read the other day that Brazil set a one day record of 3,780 COVID deaths. Just to put that in perspective using rough approximations, that would be something in the range of 40,000 COVID deaths in one day in the US. I think perhaps Trump's pal Jair Bolsonaro might want to revisit his response to the pandemic, but he appears to be more concerned with maintaining his support by the military.

https://www.cnn.com/2021/03/31/americas/brazil-bolsonaro-military-upheaval-covid-intl-latam/index.html

On the other hand, we could discuss the role, if any, of government in public health on a theoretical level.

How do you arrive at 40,000 American deaths?  Brazil's population is 211 million against America's 330 million.  The rate would be 6,000 deaths in America not 40,000.

[Alan Klein]

While children and adolescents rarely die from COVID-19, and often exhibit no symptoms at all when infected by the SARS-CoV-2 virus, there is recent evidence that asymptomatic infections in young people may have other adverse consequences:

This somewhat complicates the risk-benefit assessment of which vaccines are most appropriate to administer to this segment of the population.

Good news for children.

Pfizer Asks FDA to Expand its Coronavirus Vaccine Authorization to Children Ages 12 to 15
https://www.usnews.com/news/health-news/articles/2021-04-09/pfizer-asks-fda-to-expand-its-coronavirus-vaccine-authorization-to-children-ages-12-to-15

[faberryman]

How do you arrive at 40,000 American deaths?  Brazil's population is 211 million against America's 330 million.  The rate would be 6,000 deaths in America not 40,000.

My mistake. I thought Brazil's population was 28 million. Turns out that is the population of neighboring Venezuela. Sill, 6000 dead a day is  a lot.

[Alan Klein]

Interesting article.  Frankly, I don't understand it.  But it seems that the shots are better than the 95% announced.

95% efficacy for COVID vaccines doesn’t mean there’s a 5% infection risk. Here’s why
https://amp.miamiherald.com/news/coronavirus/article250559589.html

[Alan Klein]

My mistake. I thought Brazil's population was 28 million. Turns out that is the population of neighboring Venezuela. Sill, 6000 dead a day is  a lot.

Well, I'm glad they're really not Americans.  WE have enough problems. 

[John Camp]

New York Times reports the official covid death toll in Russia was about 57,000 and says that number is under-reported by about...300,000. Now THAT's under-reporting.

[Robert Roaldi]

New York Times reports the official covid death toll in Russia was about 57,000 and says that number is under-reported by about...300,000. Now THAT's under-reporting.

Are they including all the murdered journalists as Covid cases? 

[Alan Klein]

New York Times reports the official covid death toll in Russia was about 57,000 and says that number is under-reported by about...300,000. Now THAT's under-reporting.

Navalny might be safer in the Gulag than Moscow.

[TechTalk]

The question for this thread would be was he vaccinated with a Promising New Coronavirus Vaccine.

[Alan Klein]

I heard Navalny was using that poison after listening to Trump go on about antiseptics.