I am not sure your question makes sense--the part about demosaicing. It's only done once--a TIF is already demosaiced. If you need to brush up on the process, Wikipedia has a good article.
Here's how I would test. Open the raw file in the software of interest and export a tif--16 bits of course. Then open both the raw and the tif in a program, such as LR, that allows side-by-side comparison. You can now compare color, dynamic range, etc to see what, if anything, has been lost.