This is quite easy to deal with, and I've written it up in previous articles on this website. In a nutshell: Download Photokit Sharpener 2 Photoshop Plugin from the Pixelgenius website. Support for the application is now discontinued, but the owners are providing it free and it works with current versions of Photoshop and Mac and Windows operating systems. I think it's still the best sharpening toolset of its kind. It has custom presets for sharpening film scans, so these are combinations of settings that have been tested. Also download a copy of NeatImage from A/B Soft; this is an application one pays for but not expensive. After sharpening, inspect the results for areas of the photo where the grain looks objectionable (if not the whole photo), put them onto a new layer with a layer mask. Run NeatImage on the layer; it will automatically analyze the image and produce a combination of settings for relatively non-destructive mitigation of grain. This application is designed for dealing with digital noise, but it works very well on film grain too, despite the fact that grain isn't digital noise. If you don't like the results it produces automatically, you can operate the program in manual mode, where there are many controls for refined identification, selection and mitigation of noise or grain; you can dial in combinations of settings and examine their impacts almost immediately till you are satisfied. Used properly, it does a good job of protecting edge sharpness.