I never consider it safe to upgrade versions until several months after they've been released so they gain the benefit of the early adopters and the varied computing environments and experience they bring to bear on the applications.
If this is the only thing wrong with Photoshop and if you don't use those particular Blend Modes, which a great many users wouldn't, you should be able to carry on using it as before. But as I said, could be prudent to wait a while.