A profile I use that has been flawless on colors in gamut has a most peculiar handling of saturated but real blue colors.
Specifically, when trying to print the color Lab(50, 0, -85) what is actually printed is Lab(33,-5,5) which is a darkish green far from the printer's gamut edge. All intents should print significantly OOG colors somewhere near the gamut boundary. In particular, Perceptual Intent should best render a smooth and pleasing transition from colors that are in gamut to those outside of gamut. This profile fails:
The three charts show hue shift from a gradient that goes from Lab(50,0,0) to hues evenly spaced at 10 degree intervals from 0 to 350 degrees.
Note the extreme deviation of the 270 degree hue on the left hand charge (Perceptual Intent) as saturation increases. It actually wraps around most of the left hand side of the a*,b* area before returning.
The gradients below each chart show how each intent renders the blue gradient. The perturbation in the Perceptual intent gradient rendering is underlined.
I would never normally encounter this sort of thing as I typically use Rel. Col. and almost always stay inside the gamut. But it might cause some strangeness for those using ProPhoto and bumping up saturation. This does show up on soft proofing which matches the print so at least the profile is reporting its errant behavior correctly.