I don't have a Quattro, just the older DP2M. SPP is not a great piece of software, but it functions tolerably on a PC. It's slower than Lightroom, but the Mac delays mentioned in both reviews just aren't something I ever see on my old Core2Quad with only 8G of RAM. I've never shot even a single jpg. I've done about 2,500 total shots in 11 months, all raw.
I guess I treat that camera sort of like a 4X5 with no movements. I choose my shots pretty carefully, then get out a tripod and go to work. Sure, the screen is terrible, but it's no worse than an upside down, reverse image ground glass. I hear the sensor is only good up to 400 ISO, but since mine is always on a tripod, I've never shot over 200 anyway.
The results come with the same frustrations I remember from 4X5. A lot of times I get perfectly exposed shots that have some niggling composition problem, resulting from my not being able to see the screen well in the sun. Like maybe a tree branch that goes right to the edge of the frame. I really need to coble up a hood arrangement.
When everything goes right, the TIFF files out of SPP are remarkable. Very little tweaking required in Adobe apps. On a recent trip, I took 2,200 shots with my 6D, and about 300 with the DP2M. I printed my favorite six shots from the trip, all from the DP2M files. One sold immediately, two others are in a local show (and one of those sold right away). The other three are going on my own walls.
I'm interested in the Quattros, but only if firmware updates give it the ability to noticeably increase resolution over the Merrills. It would be great if Sigma came up with Foveon cameras that behaved like all the other cameras we have now. Believe me, I understand the pain. But they're still productive cameras, provided you're willing to use them in very specific ways.
Not exactly a ringing endorsement, I suppose.