If you use Lightroom, then you can use any plug-in or application that will generate a 32bit TIFF to produce HDR data that can be toned in Lightroom itself. As of LR 4.1, Lightroom (and the corresponding version of ACR) will accept 32bit TIFFs and extend the exposure controls to +/- 10 stops.
Disregarding the "single shot HDR", there are basically two approaches to extending dynamic range by shooting a sequence of exposures - either your merge your exposures into a single LDR image (often called exposure blending, like Enfuse or manual techniques in PS) OR you merge your exposure sequence into a single HDR file that is true, HDR 32bit data.
In the latter approach, you need to compress the tonal range of the HDR data, often called "tone mapping." With the former approach, the tonal range of the scene is compressed inherently by blending the well exposed pixels from each exposure in the sequence.
In either case, you can bring the result of your merge (the LDR enfused version or the HDR 32bit TIFF) back into Lightroom for toning, if that is the way you want to go.
Many of the above-mentioned HDR applications (Enfuse [via LREnfuse], Photomatix, HDREfex, etc.) have Lightroom plug-ins that will perform the merge and return the result to Lightroom.
One downside of using a Lightroom-based workflow to tone true HDR files is that you must use the 32bit TIFF file format, which is bloated and creates large files (as opposed to EXR).