I used (and very much liked) a Razer Naga. When Razer stopped updating the drivers, I switched to the Logitech G600. The only problem I've had is that in some apps it doesn't start tracking until after the mouse is moved (this is a known short-coming).
For "easy" work, I rely on my MacBook's built-in trackpad, which I use two-handed (right hand for movement and gestures; left for clicking). For long work-sessions, I use an Intuos 4.
Each of those benefits from careful customization and acclimatization.