Another one of 101 possible concepts:
Pelican laptop case with 1/4-20 female socket in center, reinforced on inside with 1/4" plywood or aluminum secured to base of Pelican (screws, fiberglass resin/epoxy, etc) for tripod mounting. The idea is that there is no 1/4-20 stud sticking out of case bottom to become a PITA.
Secure the laptop base to the bottom of the case (foam inserts around it of course) with 3M's velcro-style fasteners (can't recall name- like velcro on 'roids). Have ability to secure backside of open screen to inside lid of Pelican case as well.
The idea is that should the tripod topple with the lid open, the laptop and it's screen are held within the confines of the case and as protected as possible.