Hi David – – I've never used to multi-exposure mode but I gave it a shot just because your question. It seems to be a in camera attempt at exposure bracketing automaticly, I tried it with six exposures set to auto against one exposure normally. The D800e did expose six frames and then put them together resulting in one frame, but to tell you the truth there was hardly any difference other than the exposure bracketed image looked a little cleaner as far as base noise goes. There's a way to set the exposure for each frame manually which I didn't do but might be more productive. Best way to try it is to multiple test shots with your jewelry, my gut feeling is it would be tedious to do this on 60 shots. Especially when you might have to use focus stacking anyways. When shooting jewelry it seems to be a very controlled lighting situation that probably wouldn't need multi-exposure mode .
Dennis