I just returned from a week in the mountains of Nicaragua with this camera and thought some might like to hear my experiences. All in all, I continue to be extremely impressed with this kit (I took a G2 to Alaska last year).
I had 3 lenses, the 7-14mm, the 14-45 mm, and the 100-300mm. This left a hole in my focal length range, but I felt that taking a 4th lens, the 45-200mm, but I felt it wasn’t worth the extra bulk and weight (plus, it would fit in my case with the other equipment). I really wanted the long lens for birds. So, I had 14-90 mm (equivalent) for landscapes and general purpose and up to 600mm (equiv) for wildlife – and, importantly, the long lens has image stabilization which allowed many handheld shots that would not have been possible otherwise.
The whole kit, with a few filters and 3 batteries, was quite compact and lightweight. This was an important factor on long hikes on jungle trails, often steep and usually muddy. I would usually keep the 14-45 on the camera and the 100-300 in a raincoat pocket to allow quick lens changes without the need to take my pack off. With 16 megapixels and the excellent quality of the lenses, I am very happy with the images I brought back. I cannot imagine doing this trip with the equivalent capabilities in a full-frame DSLR. Here are a few images; the birds are a crimson-collared tanager and a rufous tailed hummingbird.