Ok, More to report as I played with a few options this morning.
I decided to print an image and play with the different options (based on what's available), etc. Here's what I've discovered; most of which makes sense to me.
1) When I open LR (2.2) and open an image in the Print Module, if I pull up the Print Dialogue box, I am able to go down to the lower section (separated by the horizontal line) into Paper settings. Here, besides setting the paper, you can choose the color options. It appears that the HP driver determines what is available here. If you have not chosen anything on the right printer pane in the Print Module (meaning you have not chosen any icc profiles) you can choose options on color management (Let Application, Let Printer, etc).
2) HOWEVER, if you choose a specific icc profile (so, for example I chose a new profile I made using the HP Printer Utility, "HP Z3100, Moab Photo Lasal Matte") in that right side panel, and then go into the Print button section and go to Paper settings, there is no option to determine what color management to use. My hunch is that because an icc profile has been selected, you simply do not get the option to determine how color is managed. HP print driver allows LR to override it and basically says, "Fine, if LR is managing color using an icc profile, I'm not going to allow double color management."
3) To check this, I then went up to the Color Matching dialogue option(in the top section of the Print Dialogue, above the horizontal Line) and checked to see what options, if any, there are there. They, to be expected, were grayed out with Color Sync selected and Vendor open, with no way to change. This seems to confirm to me that again, LR overrules HP driver and determines that the icc profile selected will be used and nothing else (meaning Vendor/HP Printer) can do anything about it.
I printed my test image and the colors came out as I wanted/expected.
So, although quirky, I think that LR and HP Printer Drivers work together to eliminate options for double color management.
4) On the other hand, if you choose "Managed by Printer" on the right side and then go into the Print Button Dialogue, you can then go into Color Matching, choose how you want things set up Color Sync (and then choose what icc profile, color space, etc) in the paper section OR choose Vendor Matched (and then your options are again disabled in the paper section.
For me, it appears the best settings right now, in my limited testing (I've had the printer for 1 week) is to use the LR right side menus to choose the correct icc profile (which I make using the z3100) and then in the Print Dialogue, allow ColorSync (as it's grayed out) and then make sure I've chosen the correct paper in the paper setting. Color Management is disabled and the dialogue box tells you as much if you go into the color section of the paper setting area.
I'm not sure this makes sense, but I've had no crashes and paper/colors seem to be coming out as expected.
-Josh