Wait at least 24 hours. You should not be able to smell the ink. Whether to spray both sides depends on your goal. For UV protection, no; for humidity sealing AKA vapour barrier (to whatever degree it can do this), yes.
Print Shield is essentially a lacquer, what artists call a fixative; artists who work in pastel have been spraying fixatives on their pictures for hundreds of years.
A bit of warning, FWIW: the same company that markets Print Shield also markets Eco Shield. Print Shield is a spray-on, just like an artist's fixative; but Eco Shield is a brush-on or roll-on product. I've been told that it's
much more difficult to avoid streaking and other problems with brush-ons or roll-ons; I suspect it's really intended for experienced professionals.
Another reason to consider Print Shield over Eco Shield is that we have the Henry Wilhelm longevity figures for Print Shield, not for Eco Shield ... or at least that was the case back in the old days when I was still able to navigate his site.
Ernest Dinkla wrote:
Either too close and the spray is sucked up and changes the texture/black or too far and it sets like dew on the surface.
FWIW, I've never had a problem with this using Print Shield. Simply by following the directions on the can as to spraying height and speed. The one thing you have to determine by experiment is how many coats you can apply before matte blacks begin to fog over.