Here's what I do, but I'm not sure it's much different. Maybe a few details that matter are.
Do as much processing in Lightroom as possible (from raw), except I do no sharpening at all. Export as 16-bit PSD, sRGB, longest side 600 or 800 (depending on where I'm going to post it).
In Photosop, run PK Sharpener twice, once for capture and once for web output. Then change to 8-bit and save as either:
1. Highest possible JPEG quality, for posting on my site, or
2. Auto file size to 200KB, as that's the limit on another site I use.
One of my sides corresponds exactly to a drop-down in PK Sharpener (600 or 800), but the other never does. I don't know to what extent the choice (600 or 800) matters.
I have definitely seen a difference between output sharpening for the web and not. Example on my
blog.
--Marc
basepath.com