My config: CS3 Standard installed under Windows XP. Had to run the clean script from Adobe to get it installed, and I still have outstanding issues.
One of the weirdest ones is: Upon closing Bridge, it will APPEAR as if the program is closed, but in point of fact a cursory look at Task Manager will show that it is still actually running! AND, using up memory.
And in regards to its memory usage, if you use some type of nested folder structure (as most here I suspect do) as you browse from folder to folder to folder, memory usages goes up...and up...and UP. I've seen as high as 1/2 a gigabyte of RAM.