I have a Canon Pro-2100 now and an ipf6400 before. One thing I know is that I may not use these printers for months without worrying much about getting a problem with the print head. Actually with ipf6400, once I left the printer unused for more than six months. I even turned it off for 4 months or so in the meanwhile. The printer eventually got back to work after turning it back on. It first gave a printhead error message asking to replace it. However, the problem turned out to be due to something else. One of the ink cartridges ran out of ink. Once I replaced that cartridge, the printer did its normal cycling and after 10minutes or so, it was back to work and the error message was gone.
I have never used an Epson printer. From the reports I read online, I don't dare buying them since I know I am never going to be a regular printer user meaning I may very well run into problems with them. PS: I know the Epson printers vary and some are more tolerant than others if not being used for a while. I still trust Canon printers over any Epson printer on this matter.