Thanks for the replies, friends
In the meantime I discovered that the application ran well if I did it "as Administrator".
I'm using a new PC and had many Apps reinstalled.
In this case I located the file, opened Properties-Shortcut-Advanced and checked "Run as Administrator"
This seems to have solved the problem.
I don't know why this is so and had never had it in the old PC (also W10) but anyway...
FWIW