My 2 cents after about 4 hours and 20 images:
No tech problems on my Win10 desktop with I7 processor, 16gb main memory and Nvidia GTX 960 GPU. It did crash immediately on the first attempt to run as a Photoshop plugin. But then I ran the stand alone which did the trail license dialogue. After that the Photoshop plugin runs OK. I was a little confused that it's not part of Studio.
The UI was initially confusing. There are 3 "Processing Modes", Sharpen, Stabilize, and Focus. Are the stackable? Can you apply all 3 to different degrees in one process? The answer seems clearly NO. It's one and one only.
Noise suppression and grain addition are useless here. You are much better off dealing with these before and after AI Sharpen. Don't know why Topaz included them.
SHARPEN gives some good results, but not as good and not as convenient as many other tools, including Topaz' own Detail tool.
FOCUS failed to produce usable results on all my tests. It would produce strange artifacts in areas immediately adjacent to areas where nothing was done. I went thru many shots that were definitely out-of-focus and not camera shake or subject movement. The Focus process failed to produce any usable results. When it came close it would be only in small areas that would require extensive manual masking. On shots with shallow DOF, the FOCUS setting to get the best foreground would literally destroy the out-of-focus (bokeh) background.
STABILIZE does some very good and surprising things. However, it too would ignore some small areas and give bad artifacts in other small areas, leading to more extensive manual masking. It did a much better job than FOCUS at restoring out-of-focus images. On portraits, the setting used to get good eyes would produce ugly artifacts in hair. On angled face shots, the best setting for the near eye didn't work well on the far eye. So two passes and masking was needed - at 3 to 5 minutes per pass.
Some Annoyances: There is no "sticky" logic. Every time you launch all settings are at default. In the stand alone, the Save-As defaults to 16bit Tif in sRGB with LZW compression, regardless of the attributes of the input Tif. LZW + 16bit is a definite no-no.
Conclusion: Not ready for Prime Time, but STABILIZE shows some promise for the future.