The scans need to be sharpened, but I wouldn't recommend doing that from scan software even though most of those products provide sharpening tools. The reason is that once you sharpen at the scan stage, that sharpening is baked-in and you can't change it unless you rescan, which is a nuisance. As well, the sharpening tools in scan software don't use the three stage sharpening work flows that Bruce Fraser introduced us to years ago, make so much sense and work very well, especially for film scans - Photokit Sharpener for example has an in-built sharpener at the Capture sharpen stage for film scans, which is also adjustable, adaptable and non-destructive s long you retain the sharpening layers. Sharpening film scans in LR is also a good option.