Thank you, Andrew.
For purposes of this thread (where I'm not talking about saving jpegs where compression is an issue), I save my .psds as psds all the time, so I gather that compression choices are not an issue for them. Is that right?
If I understand your reply, for purposes of seeing which files are bloated -- e.g. I may have saved a lot of channels I don't need to keep because I have the corresponding layer masks and so could save the channels again if necessary, or maybe delete some no-longer-useful merged layers from intermediate steps -- I can pay attention to only the file size numbers in the finder.