I'm a big fan of Qimage as well. But... for large prints (in my world, thats anything over 13x19) I prefer Photokit Sharpener over the built in sharpening options in Qimage. You can still use QI to uprez, then just print to a file, sharpen, then print. I think the uprezzing in QI is pretty well state of the art.
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I use PK also, but it merely increases perceived sharpness. The Richardson-Lucy algorithm can actually restore image detail. It was used in the Hubble telescope images before the instrument was fixed. This algorithm is discussed on Roger Clark's web site. He says that the print size can be doubled with this technique. Beware, the method is quite slow.
[a href=\"http://www.clarkvision.com/imagedetail/image-restoration1/index.html]http://www.clarkvision.com/imagedetail/ima...ion1/index.html[/url]
The RL algorithm is available in the freeware astronomy image processing program
IRIS. I think that smart sharpening in PS also uses a deconvolution method and can be useful if you use the right parameters. However, Bruce Fraser reports that it is of limited value in his sharpening book. I have not used either method and would be interested in hearing from those who have.
Bill