Closely followed by the loss of the ability to play with controlled filter effects in the computer (while you’re converting to black/white) because there no are colours with which to play.
I’ve looked at a lot of black/white-type sensor photos online, and it’s difficult to accept that that type of capture always leads to the best look. There seems to be a general weakness in the highlights areas, with loss of detail apparent in what I might have considered important areas. (Okay, perhaps user over exposure error, but that’s kinda beyond the limits of reasonable deconstruction of the photo.)
If I were to be interested in printing, maybe the files might look a bit crisper, but for me at least, that era has been and gone.
Frankly, the fewer limits your camera imposes, the better. Which is not to say I’m much of a fan of having a machine capable of miracles, when all I want to do is take advantage of auto ISO if I want it, and autofocus because my eyes are not as they were. Some form of stabilisation would help, especially when going beyond a 50mm lens, but of my cameras, only my iPhone has that - as far as I know.