Andrew,
What is your advice when sending a file to a lab that has profiles downloadable? To send them a file with ProPhotoRGB (alternatively AdobeRGB or even sRGB) or to convert to a printer/paper profile and the rendering intent of choice? In this particular case, we are talking about a "direct print on brushed aluminum" CMYK profile by White Wall lab, which I assume has a gamut even smaller than sRGB.