I have a very lightly used E-4900 printer. I keep a small plastic tray filled with water and a utility sponge in it to keep the internal humidity high and reduce (but not eliminate) drops/clogs. You can reference some of my earlier posts for pics and details. I usually am able to recover any line gaps with a regular cleaning. However today, after noting a couple of gaps in my Cyan and VM channel, after the paired channel cleaning run Cyan was perfect, and the VM was totally gone. I sent from just a few gaps to 100% blank. I ran a letter-size print of the VMchannel-only file from marruttusa.com. I do not yet have the service program, and wasn't yet at the point where I felt I needed to run a line-charging to try to recover, so this seemed like my best option to try to get the line recharged, or the air bubble cleared. I'd considered doing the printer off-on cycle again to try to re-pressurize the carts, but wanted to try this first. Marruttusa has a series of files that print an image of a single color channel only. Interestingly, this print was perfect-no banding, nice solid color throughout. I ran another nozzle check, and again the VM channel was completely blank. Having run a couple of prints now , I did another cleaning and had the image seen in 1520 below, and again using a file from marrutusa com that prints a row of single-channel colors I wound up with what's seen in 1521. I did not run the single-channel file again. Clearly issues with banding from the VM channel. Ran another cleaning of the Cyan/VM pair, and got the much better (but not yet perfect) nozzle check result in 1522 (note the gap in the top row just off center and the bottom row at the very right side), and the marrutta file print seen in 1523. This still shows some banding, but is much improved. Ran a 4th paired cleaning after these prints and now have perfect results.
My take home lesson here would be if after a cleaning you have a dropped channel...don't panic. Run test prints (I have several others that I use on a randomly rotating basis), continue to cycle 1 or more prints followed by cleaning cycles and nozzle checks, and have some patience.