Frankly I always attributed the loss of IQ as being part of the 16MP sensor when cropped to 100%. But handheld I've always had amazing results with mine. My d810 doesn't produce this quality handheld unless I really crank the shutter speed up, but then of course I've got to shoot at lower F stops or higher ISO.
This image is f/13, 1/350, ISO 200, -1.3 exposure, 164mm - 246mm Equivalent, handheld.
In my general analysis, I'd like to be able to see the craters on the moon here when I zoom in and I cannot. This poses the question to me, if I shot this same shot with the exact same settings on my d810, would I see the craters? Or is it simply that the tree is in focus and the background is not? Could I have shot this better on the fuji by focusing for the moon, or infinity at f16 and introducing the resulting diffraction?