Testing on your own system is always the best way to try things.
Behind my computer is a 30x20 inch print created with my D700. The image is cropped down about 20% from the original image. It has hung on the wall for about 2 years and in digital terms, this is timeless. I probably up-rezzed the photo using Photoshop. The print file, though, is at 180 ppi which looks fine on large prints. On my equipment and printer the image is superb and my mentor and colleagues confirm this.
The photo was taken with my D700, 17-35mm zoom probably at 1/30th at f3.5 hand-held in a dark monastery in Serbia. The iso was pumped up to 4500 since the monastery is 800 years old and technology there is minimum. Everything about the image tells me it is a failure if only the numbers mattered. But the heart and soul of the image combined with good craft makes this a winner and the print on my wall is the witness.
I stopped doing the math on my images many years ago and now rely upon the print as the final test. If the image can't reproduce well as a 13x19 image as a minimum it will seldom go further than my trash after archiving. There are exceptions, but they've got to stand out.