A stitcher since 2003 or so, I have used all of the various software solutions.
I don't believe CC has updated their code since around CS5 levels, as Bart mentioned. I find it Ok for single row work but multi row and it tends to get bogged down, and takes way too much ram. (this is on a 32GB i7 win7 64 bit).
Many forget the version that was available in CS3, where you could actually move the segments around in the "reposition" selection. With CS4 this went away at least I have never been able to move them anymore. The CS3 version (even extended) was limited by total ram available as it was not a 64 bit app, thus using this option on 16 images never worked, as the program choked.
PtGui, has a ton of power and after you get used to the interface and control point layout, does a a good job most of the time. Make sure you check the advanced tab as it gives you so many more options, and look selection for interpolation as PtGui offers a huge number of them. CC doesn't give you any options and I have read it still uses nearest neighbor in the panoramic process. I had hoped this would be improved with CC or CC 2014 as in the standard uprez tab, they did add a new (enlargement preserve details) selection which does very well.
Kolor's solution also can work wonders.
I never send raws in, always adjusted tif files, but that's my preference just seems to give me better balance output. Plus a lot of stuff I am working with is MFD stitched, needing an LCC correction.
Paul