The odd thing with the eyes is that her pupils are constricted, suggesting a lot of light falling on her, yet her eyes are wide open - I'd say that we don't often see the two together. Those constricted pupils also suggest that she's not afraid; fear stimulates a fight/flight/freeze response, and floods the body with adrenaline, which causes pupils to dilate. She's also looking directly at the viewer. This suggests interest, but an accompaniment to interest is dilated pupils (again), and of course her's are constricted. I'd say there is enough confusion in the non-verbal communication here to cause the viewer a certain amount of unease.
That's this psychologist's tuppence worth. YMMV