That's true, because 13 inches is a bit wider than the width span that the measurement ruler allows, so the wastage in that sense is higher. Sorry, I forget about these width issues with cut sheets because I only print off rolls these days. But try arranging 1457 patches across three 8.5x11 sheets. 5.2 patches/sq inch.
The perceptible differences, with i1Profiler's ingestion engine, is small. Measurement errors do cause far more significant issues. So for most its not worth bothering about.
I simply looked at the RGB reference values. You can save out from the "Patch Set" or "Test Chart" module. Visualizing with 3D modelling software is tricky. For example, 128, 127, 128 will look pretty close to 128, 128, 128 in a roughly evenly sampled RGB cube with the samples plotted as points in space, I doubt you can pick that out. Looking at the actual values itself is also highly informative of other under-the-hood calculations X-rite is making for their "smart" targets.