Thanks for the reply's.
Unfortunately the trees now have leaves, so a re shoot isn't possible, but I didn't mention that this was going to be black & white in the end. I've looked at the channels, and I think that a mask might be the way to go, and combine that with careful cloning.
Any time spent will be worth it as I've all ready have at least 20 hours in this project. This pano is made up of 60 images with 3 vertical columns 10 degrees apart, and rotated 5 degrees horizontal, 85mm Nikkor lens @f8, with 3 exposures per image for HDR.
This pano is a down town city street taken late at night. There are NO car's headlights, NO cars anywhere in the picture at all by design, this made for a long night (over two hours) to shoot this, and I've already re shot parts of it 4 times now. There many street lights with lots of flare, but having a lot of overlap (50%) has allowed me to edit out most of the flare using masks made from adjacent shots, because of the rotation of the panohead, the axis of the lens changes just enough to eliminate the flare in adjacent shots, but in this frame, there isn't anything to make a mask from.
BTW, Its just a hobby.