Test and measure to your heart's content. For me, what I use isn't key to my work or my success, though at times, it does help. The most important aspect to me is the end product--web, print or publication.
If one is happy with the results and is successful, the method and the tools to get there are irrelevant. Few ever cared the brush used by Rembrant or the etching press used by Picasso. It's the final artwork that counts!
Fair enough, but many of the most expensive paintings made in the modern era have particularly well-controlled color, as opposed to earlier eras, where strong draftsmanship was a minimum requirement. MF cameras produce stronger color rendition than 35mm cameras, so this (I think) is not the same as a brush to a painter. It is more like the difference between the use of encaustic paint and oil paint. Color was revolutionized in the nineteenth century because of new methods of manufacturing oil paint and this radically altered the palettes used by artists from that date on. Before that, the range of colors available was considerably limited in comparison. Collectors might not care what paint was used, but they do care if they like the color in the image.
AP