Here's another possibility.
I use two monitors, but generally only use the main monitor for LightRoom. I have shortcuts to my frequently used programs, including LR, on the second monitor. In the past, when I double-clicked the shortcut on the second monitor, LR would open on my main monitor, as I preferred. But somehow, with the upgrade to LR 4.4, it started opening on the second monitor instead.
My solution was to make a copy of the shortcut on my main monitor and now I open LR from there, and I get what I want.
Since this behavior only occurs with LR 4.4, it does seem as if LR is now using the shortcut location instead of the control panel settings to decide where to open.
Weird and annoying! I hope one of these ideas helps.
Eric M.