Yes there is. Use a professional noise reducing plug-in, such as Topaz DeNoise, Noise Ninja. Neat Image or Noiseware. There are frequent recommendations for Neat Image when it comes to cleaning-up film scans. I agree with those recommendations, but also find that Topaz Denoise does a very good job with fewer settings. If you print from Lightroom, I would also highly recommend Lightroom's noise reduction functions.