The way it works I try to focus on what needs to be really sharp, and stop down as needed. I'm familiar with hyperfocal focusing, but I really prefer to have my main subject sharp. It happens that I put focus between two points of interest.
When shooting on tripod, which I rather do, I mostly use live view at maximum magnification.
Another option may be to use Scheimpflug, that is tilting the lens to fit the plane of sharpness to the subject. I have a few old medium format lenses with adapters that can do this.
I happen to know several professionals, with 30 year studio experience, who shot with company provided Canon 5D2 for a long time and did not know such a thing as live view existed on their cameras. They did not use video, so they never came across this feature, and as usual, did not read the manuals.