I've tried to uninstall the i1P and reinstall it but that doesn't help
i1Profiler 1.4.2 (demo) has been well behaved for me on Win-7-Pro, at least as far as the installation.
Sometimes you can "Repair" an installation rather than "Uninstall". This tends to reset to defaults, and make sure all files are present in the correct location.
Have you got "System Restore" turned on for the applicable drive? Occasionally this works to get back to a known good configuration before the install.
Have you tried Win-Xp-Mode? (virtual machine)? How about installing on another computer (in demo mode just to get to launch)?
I"ve got a "Sandbox" partition snapshot that I use to test installations. It is very "vanilla" to avoid conflicts. I generally "practice" an installation to see if it has quirks. Then I do a "real" install on my primary partition. The idea is to avoid "crud accretes" and "bit rot" from flawed installs.